New and simple synthesis of acid azides, ureas and carbamates from carboxylic acids: application of peptide coupling agents EDC and HBTU.

نویسندگان

  • Vommina V Sureshbabu
  • H S Lalithamba
  • N Narendra
  • H P Hemantha
چکیده

Conversion of carboxylic acids into acid azides using peptide coupling agents, EDC and HBTU is described. The procedure is efficient, practical and applicable to a diverse range of carboxylic acids including N-protected amino acids. Using the same reagents, one-pot synthesis of ureas, dipeptidyl urea esters and carbamates from acids has also been achieved.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 8 4  شماره 

صفحات  -

تاریخ انتشار 2010